SubtiBank SubtiBank
ispA [2018-03-20 13:50:14]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ispA [2018-03-20 13:50:14]

intracellular serine protease
Locus
BSU13190
Isoelectric point
4.52
Molecular weight
33.69 kDa
Protein length
319 aa Sequence Blast
Gene length
957 bp Sequence Blast
Function
protein degradation
Product
intracellular serine protease
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Metabolism → Amino acid/ nitrogen metabolism → Utilization of nitrogen sources other than amino acids → Utilization of proteins
  • Information processing → Protein synthesis, modification and degradation → Proteolysis → Additional proteins involved in proteolysis

    • Gene

    Coordinates
    1,386,024 → 1,386,983

    The protein

    Protein family

  • peptidase S8 family (according to Swiss-Prot)

    • Structure

  • 2WV7 (from Bacillus clausii, 53% identity) PubMed

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    ispA
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • CodY: repression, PubMed, in CodY regulon

    • Regulation

  • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • view in new tab

    Biological materials

    Mutant

  • BKE13190 (ΔyqiD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAAAAAAGCCCTCCTTTT, downstream forward: _UP4_TAAGATTATTTTTCTTATAT
  • BKK13190 (ΔyqiD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAAAAAAGCCCTCCTTTT, downstream forward: _UP4_TAAGATTATTTTTCTTATAT

    • References

    Loading